Alexander, known as Anand Jon in the industry, has pleaded not guilty to more than 40 felony and misdemeanor counts, including rape, sexual battery and committing a lewd act on a child.
Authorities said the alleged victims were 14 to 27 years old, and the incidents took place during a 4 1/2-year period between November 2002 and March 2007.
Alexander was in court Tuesday. He changed lawyers, and a judge postponed the setting of his preliminary hearing date until Sept. 26. He remains behind bars, with bail set at $1.3 million.
If convicted of all the charges, he could face life in prison.
A phone message left with his new attorney, Anthony Brooklier, was not immediately returned.
The criminal case is focused on incidents in California and Texas, where three arrest warrants were issued for the fashion designer.
Texas authorities said they plan to seek indictments for sexual assault and extradite Alexander after his California case concludes.
Investigations also are under way in New York and Massachusetts, authorities said.
Two images of the 33-year-old, India-born designer have emerged as he sits in a Los Angeles County jail cell.